The reference site for Fludrocortisone

Fludrocortisone, sold under the brand name Florinef among others, is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency.

WHAT IS Fludrocortisone?

Fludrocortisone is in a class of drugs called steroids. Your body naturally produces steroids similar to this medicine.

This particular medicine is used to treat conditions in which the body does not produce enough of its own steroids, such as in Addison’s disease, and salt-losing adrenogenital syndrome.


Brand Name(s): Florinef Acetate
CAS nº: 127-31-1
(flew droe KOR ti sone)


Product Info

The sections below will provide you with more specific information and guidelines related to fludrocortisone and its correct use. Please read them carefully.

FDA Information

Fludrocortisone has been approved by the Food and Drug Administration. A prescription is required for this medicine.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Fludrocortisone is in a class of drugs called steroids. Your body naturally produces steroids similar to this medicine.

This particular medicine is used to treat conditions in which the body does not produce enough of its own steroids, such as in Addison’s disease, and salt-losing adrenogenital syndrome.

Other uses for this medicine

This medication may also be used for certain types of low blood pressure.

Nevertheless, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Fludrocortisone comes in the form of an oral tablet.

Take this medicine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Each dose should be taken with a full glass of water, and also with food or milk to lessen stomach upset.

Try to take your dose at the same time each day.

It is advised not to stop taking this medicine suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication.

Additionally, carry some type of medical identification that will let others know you are taking fludrocortisone in the case of an emergency.

What special precautions should I follow?


Tell your doctor if you have high blood pressure or heart disease, kidney disease, liver disease, hypothyroidism, tuberculosis, diabetes mellitus, psychiatric conditions, ulcerative colitis, stomach ulcers, myasthenia gravis, osteoporosis, or any other medical conditions. You may not be able to take this medicine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Moreover, do not take this medicine if you have a serious bacterial, viral, or fungal infection. Fludrocortisone weakens your body’s immune response and thus its ability to fight infection.

Inform your doctor if you are taking any of the following medicines: a barbiturate such as amobarbital (Amytal®), secobarbital (Seconal®), pentobarbital (Nembutal®), or phenobarbital (Luminal®, Solfoton®); birth control pills (such as Ortho Novum®Ovral®Lo-Ovral®, Triphasil®Levlen®Tri-Levlen®Alesse®Desogen®, and others); an estrogen (Premarin®Ogen®Estratest®Estraderm®Vivelle®Climara®Fempatch®, and others); a diuretic (water pill) such as furosemide (Lasix®), ethacrynic acid (Edecrin®), bumetanide (Bumex®), or torsemide (Demadex®); insulin or an oral diabetes medicine such as chlorpropamide (Diabinese®), glipizide (Glucotrol®) or glyburide (Diabeta®, Glynase®, Micronase®); an anabolic steroid such as oxymetholone (Anadrol-50®), nandrolone (Durabolin®, others); phenytoin (Dilantin®) or ethotoin (Peganone®); rifampin (Rifadin®); digoxin (Lanoxin®, Lanoxicaps®); amphotericin B (Fungizone®); warfarin (Coumadin®); or aspirin. You may need a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

You should try and avoid sources of infection. Wash your hands frequently and keep them away from your mouth and eyes. Your immune system may be weakened while you are taking fludrocortisone. Notify your doctor if you are exposed to an infection such as chicken pox or measles.

Avoid immunizations during treatment with fludrocortisone unless your doctor approves it.

Tell your doctor if you are having surgery, including dental surgery. Limit your consumption of alcoholic beverages while taking this drug.

Fludrocortisone is in the FDA pregnancy category C. This means that it is not known whether this medicine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

Fludrocortisone passes into breast milk. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose.

Do not take a double dose of this medication.

What side effects can this medication cause?

If you experience any of the following serious side effects, stop taking fludrocortisone and seek emergency medical attention:

an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
swelling of the feet or ankles
difficulty breathing
severe or continuing headache
dizziness or fainting
increased blood pressure (severe headache or blurred vision)
sudden weight gain (more than 5 pounds in a day or two)

Other side effects may occur rarely, usually with prolonged courses of fludrocortisone. Talk to your doctor if you experience

nausea or stomach upset
muscle weakness or joint pain
problems with diabetes control
increased hunger or thirst
thinning of your skin
round face
changes in behavior

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Remember to throw away any medication that is outdated or no longer needed. If required, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, seek emergency medical attention by calling your local poison control center on 1-800-222-1222. If the victim has collapsed or is not breathing, then please call the local emergency services on 911.

However, a single large dose of this medication is unlikely to cause serious symptoms or death. Overdose symptoms are more likely to be caused by a chronic overdose – large doses taken over a period of time.

Symptoms of overdose may include:

swelling or water retention
high blood pressure (headache, blurred vision)
weight gain
low levels of potassium in the blood

Product Images


Below you will find images and specific information on the principal types of fludrocortisone that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 0.1 MG
Imprint: 7033
Manufacturer: GLOBAL PHARM.

Strength(s): 0.1 MG
Imprint: b | 997 1/10
Manufacturer: BARR LABS.

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